검색어 : 통합검색[Symons Julian]
총 113건 중 113건 출력
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101
- Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models
- Jekle, Andreas; Thatikonda, Santosh Kumar; Jaisinghani, Ruchika; Ren, Suping; Kinkade, April; Stevens, Sarah K.; Stoycheva, Antitsa; Rajwanshi, Vivek K.; Williams, Caroline; Deval, Jerome; Mukherjee, Sucheta; Zhang, Qingling; Chanda, Sushmita; Smith, David B.; Blatt, Lawrence M.; Symons, Julian A.; Gonzalvez, Francois; Beigelman, Leonid; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Francisco, CA 94080, USA; Aligos Therapeutics, Inc., South San Fra; (International journal of molecular sciences, v.24, 2023, pp.16274)
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102
- THU-198 In vitro and in vivo pharmacological characterization of human PNPLA3-targeting short interfering RNA molecules for the treatment of metabolic dysfunction-associated steatohepatitis
- Song, Jieun; Deval, Jerome; Adame, Lillian; Jaisinghani, Ruchika; Tso, Emily; Lin, Daniel; Bhattacharya, Aneerban; Stoycheva, Antitsa; Sousa, Jacquelyn; Parish, Craig; Montero, Saul Martinez; Rajwanshi, Vivek; Daguison, Shane; Gohil, Vikrant; Zhang, Qingling; Williamson, Toni; Chanda, Sushmita; Talukdar, Saswata; Smith, David; Beigelman, Leonid; Symons, Julian; Zhou, Yingjiang; Luong, Xuan; ; (Journal of hepatology : the journal of the European Association for the Study of the Liver, v.80, 2024, pp.S564-S565)
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103
- Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)
- Luong Xuan G.; Stevens Sarah K.; Jekle Andreas; Lin Tse-I; Gupta Kusum; Misner Dinah; Chanda Sushmita; Mukherjee Sucheta; Williams Caroline; Stoycheva Antitsa; Blatt Lawrence M.; Beigelman Leonid N.; Symons Julian A.; Raboisson Pierre; McGowan David; Vandyck Koen; Deval Jerome; ; (, v., 2020, )
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104
- An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients
- Debing, Yannick; Vanrusselt, Hannah; Degrauwe, Lars; de Oliveira, Daniel Apolô nio Silva; Kariuki, Christopher; Ebwanga, Ebanja Joseph; Bashir, Shahbaz; Merckx, Wouter; Thatikonda, Santhosh; Gohil, Vikrant; Smith, David; Raboisson, Pierre; Montero, Saul; Hong, Jin; Sanchez, Abel Acosta; Blatt, Lawrence; Symons, Julian; Lin, Tse-I; Beigelman, Leonid; Paeshuyse, Jan; ; (Journal of hepatology : the journal of the European Association for the Study of the Liver, v.78, 2023, pp.S1051)
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105
- The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture
- Klumpp, Klaus; Lé vê que, Vincent; Le Pogam, Sophie; Ma, Han; Jiang, Wen-Rong; Kang, Hyunsoon; Granycome, Caroline; Singer, Margaret; Laxton, Carl; Hang, Julie Qi; Sarma, Keshab; Smith, David B.; Heindl, Dieter; Hobbs, Chris J.; Merrett, John H.; Symons, Julian; Cammack, Nick; Martin, Joseph A.; Devos, Rene; Ná jera, Isabel; ; (The Journal of biological chemistry, v.281, 2006, pp.3793-3799)
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106
- Discovery and Preclinical Profile of ALG-055009, a Potent and Selective Thyroid Hormone Receptor Beta (THR-β) Agonist for the Treatment of MASH
- Vandyck, Koen; McGowan, David C.; Luong, Xuan G.; Stevens, Sarah K.; Jekle, Andreas; Gupta, Kusum; Misner, Dinah L.; Chanda, Sushmita; Serebryany, Vladimir; Welch, Michael; Hu, Haiyang; Lv, Zhidan; Williams, Caroline; Maskos, Klaus; Lammens, Alfred; Stoycheva, Antitsa D.; Lin, Tse-I; Blatt, Lawrence M.; Beigelman, Leonid N.; Symons, Julian A.; Raboisson, Pierre; Deval, Jerome; Aligos Belgium BV , Gaston Geenslaan 1 , 3001 Leuven , Belgium; Aligos Therapeutics, Incorporated , 1 Corporate Drive , South San Francisco , California 94080 , United States; Aligos Therapeutics, Incorporated , 1 Corporate Drive , South San Francisco , California 94080 , United States; Aligos Therapeutics, Incorporated , 1 Corporate Drive , South San Francisco , California 94080 , United States; Aligos Therapeutics, Incorporated , 1 Corporate Drive , South San Francisco , California 94080 , United States; Aligos Therapeutics, Incorporated , 1 Corporate Drive , South San Francisco , California 94080 , United States; Aligos Therapeutics, Incorporated , 1 Corporate Drive , South San Francisco , California 94080 , United States; Aligos Therapeutics, Inco; (Journal of medicinal chemistry, v.67, 2024, pp.14840-14851)
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107
- ALG-097111, a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease inhibitor exhibits in vivo efficacy in a Syrian Hamster model
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Vandyck, Koen;
Abdelnabi, Rana;
Gupta, Kusum;
Jochmans, Dirk;
Jekle, Andreas;
Deval, Jerome;
Misner, Dinah;
Bardiot, Dorothé
e;
Foo, Caroline S.;
Liu, Cheng;
Ren, Suping;
Beigelman, Leonid;
Blatt, Lawrence M.;
Boland, Sandro;
Vangeel, Laura;
Dejonghe, Steven;
Chaltin, Patrick;
Marchand, Arnaud;
Serebryany, Vladimir;
Stoycheva, Antitsa;
Chanda, Sushmita;
Symons, Julian A.;
Raboisson, Pierre;
Neyts, Johan;
Aligos Belgium BV;
Rega Institute for Medical Research, KU Leuven;
Aligos Therapeutics, Inc.;
Rega Institute for Medical Research, KU Leuven;
Aligos Therapeutics, Inc.;
Aligos Therapeutics, Inc.;
Aligos Therapeutics, Inc.;
CISTIM Leuven vzw;
Rega Institute for Medical Research, KU Leuven;
Aligos Therapeutics, Inc.;
Aligos Therapeutics, Inc.;
Aligos Belgium BV;
Aligos Belgium BV;
CISTIM Leuven vzw;
Rega Institute for Medical Research, KU Leuven;
Rega Institute for Medical Research, KU Leuven;
Centre for Drug Design and Discovery (CD3), KU Leuven
Belgium
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108
- Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate
- Deval, Jerome; Hong, Jin; Wang, Guangyi; Taylor, Josh; Smith, Lucas K.; Fung, Amy; Stevens, Sarah K.; Liu, Hong; Jin, Zhinan; Dyatkina, Natalia; Prhavc, Marija; Stoycheva, Antitsa D.; Serebryany, Vladimir; Liu, Jyanwei; Smith, David B.; Tam, Yuen; Zhang, Qingling; Moore, Martin L.; Fearns, Rachel; Chanda, Sushmita M.; Blatt, Lawrence M.; Symons, Julian A.; Beigelman, Leo; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alio; (PLoS pathogens, v.11, 2015, pp.e1004995)
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109
- An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients
- Debing, Yannick; Vanrusselt, Hannah; Degrauwe, Lars; Silva de Oliveira, Daniel Apolô nio; Kariuki, Christopher Kinyanjui; Ebwanga, Ebanja Joseph; Bashir, Shahbaz; Merckx, Wouter; Thatikonda, Santhosh Kumar; Rajwanshi, Vivek; Gohil, Vikrant; Hong, Jin; Kum, Dieudonné Buh; Acosta Sanchez, Abel; Chanda, Sushmita; Blatt, Lawrence M.; Jekle, Andreas; Symons, Julian A.; Smith, David B.; Raboisson, Pierre; Lin, Tse-I; Beigelman, Leonid; Paeshuyse, Jan; ; (Antiviral research, v.224, 2024, pp.105835)
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110
- The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor <i>In Vitro</i> and Confer Resistance To Nirmatrelvir
- Jochmans, Dirk; Liu, Cheng; Donckers, Kim; Stoycheva, Antitsa; Boland, Sandro; Stevens, Sarah K.; De Vita, Chloe; Vanmechelen, Bert; Maes, Piet; Trü eb, Bettina; Ebert, Nadine; Thiel, Volker; De Jonghe, Steven; Vangeel, Laura; Bardiot, Dorothé e; Jekle, Andreas; Blatt, Lawrence M.; Beigelman, Leonid; Symons, Julian A.; Raboisson, Pierre; Chaltin, Patrick; Marchand, Arnaud; Neyts, Johan; Deval, Jerome; Vandyck, Koen; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Virology & Chemotherapy, Leuven, Belgium; Aligos Therapeutics, Inc., South San Francisco, California, USA; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Virology & Chemotherapy, Leuven, Belgium; Aligos Therapeutics, Inc., South San Francisco, California, USA; CISTIM Leuven vzw, Leuven, Belgium; Aligos Therapeutics, Inc., South San Francisco, California, USA; Aligos Therapeutics, Inc., South San Francisco, California, USA; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Clinical & Epidemiological Virology, Leuven, Belgium; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Clinical & Epidemiological Virology, Leuven, Belgium; Institute of Virology and Immunology, University of Bern, Bern, Switzerland; Institute of Virology and Imm; (mBio, v.14, 2023, pp.e02815-22)
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