검색어 : 통합검색[Cancer drug discovery and development]
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981
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Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3)
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Abdel-Rahman, Somaya A.;
Rehman, Ashfaq Ur;
Gabr, Moustafa T.;
Department of Radiology, Molecular Imaging Innovations Institute (MI3) , Weill Cornell Medicine , New York , New York 10065 , United States;
Department of Molecular Biology and Biochemistry , University of California, Irvine , Irvine , California 92697 , United States;
(ACS medicinal chemistry letters,
v.14,
2023,
pp.629-635)
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982
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Developmental Therapeutics Program at the NCI: molecular target and drug discovery process
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Monga, M;
Sausville, EA;
;
(Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K,
v.16,
2002,
pp.520-526)
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983
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Systematic Exploration of Privileged Warheads for Covalent Kinase Drug Discovery
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Zhao, Zheng;
Bourne, Philip E.;
;
(Pharmaceuticals,
v.15,
2022,
pp.1322)
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984
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Microfluidic co-cultures with hydrogel-based ligand trap to study paracrine signals giving rise to cancer drug resistance
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Patel, Dipali;
Gao, Yandong;
Son, Kyungjin;
Siltanen, Christian;
Neve, Richard M.;
Ferrara, Katherine;
Revzin, Alexander;
Department of Biomedical Engineering;
Department of Biomedical Engineering;
Department of Biomedical Engineering;
Department of Biomedical Engineering;
Department of Discovery Oncology;
Department of Biomedical Engineering;
Department of Biomedical Engineering;
(Lab on a chip,
v.15,
2015,
pp.4614-4624)
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985
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Phytoconstituents and Medicinal Plants for Anticancer Drug Discovery: Computational Identification of Potent Inhibitors of PIM1 Kinase
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Anjum, Farah;
Mohammad, Taj;
Almalki, Abdulraheem Ali;
Akhtar, Omar;
Abdullaev, Bekhzod;
Hassan, Md. Imtaiyaz;
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.;
Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.;
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.;
Department of Medicine, Tbilisi State Medical University, Tbilisi, Georgia.;
Scientific Department, Akfa University, Tashkent, Uzbekistan.;
Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India.;
(Omics : a journal of integrative biology,
v.25,
2021,
pp.580-590)
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986
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Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors
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Dong, Guangping;
Yasgar, Adam;
Peterson, Darrell L.;
Zakharov, Alexey;
Talley, Daniel;
Cheng, Ken Chih-Chien;
Jadhav, Ajit;
Simeonov, Anton;
Huang, Rong;
Department of Medicinal Chemistry and Molecular Pharmacology, Center for Cancer Research, Institute for Drug Discovery , Purdue University , West Lafayette , Indiana 47907 , United States;
National Center for Advancing Translational Sciences , National Institutes of Health , Rockville , Maryland 20892 , United States;
Department of Biochemistry, Institute for Structural Biology, Drug Discovery and Development , Virginia Commonwealth University , Richmond , Virginia 23219 , United States;
National Center for Advancing Translational Sciences , National Institutes of Health , Rockville , Maryland 20892 , United States;
National Center for Advancing Translational Sciences , National Institutes of Health , Rockville , Maryland 20892 , United States;
National Center for Advancing Translational Sciences , National Instit;
(ACS combinatorial science,
v.22,
2020,
pp.422-432)
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987
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Patient-Derived In Vitro Models for Drug Discovery in Colorectal Carcinoma
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Ramzy, George M.;
Koessler, Thibaud;
Ducrey, Eloise;
McKee, Thomas;
Ris, Fré
dé
ric;
Buchs, Nicolas;
Rubbia-Brandt, Laura;
Dietrich, Pierre-Yves;
Nowak-Sliwinska, Patrycja;
Molecular Pharmacology Group, School of Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva, Switzerland;
George.Ramzy@unige.ch (G.M.R.);
Eloise.Ducrey@unige.ch (E.D.);
Department of Oncology, Geneva University Hospitals, 1211 Geneva, Switzerland;
Thibaud.Kossler@hcuge.ch (T.K.);
Pierre-Yves.Dietrich@unige.ch (P.-Y.D.);
Molecular Pharmacology Group, School of Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, 1211 Geneva, Switzerland;
George.Ramzy@unige.ch (G.M.R.);
Eloise.Ducrey@unige.ch (E.D.);
Division of Clinical Pathology, Diagnostic Department, University Hospitals of Geneva (HUG), 1211 Geneva, Switzerland;
Thomas.A.McKee@hcuge.ch (T.M.);
Laura.Rubbia-Brandt@unige.ch (L.R.-B.);
Translational Department of Digestive and Transpla;
(Cancers,
v.12,
2020,
pp.1423)
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988
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Response biomarkers: re-envisioning the approach to tailoring drug therapy for cancer
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Amin, Shahil;
Bathe, Oliver F.;
Cumming School of Medicine, Faculty of Graduate Studies, University of Calgary, Calgary, Canada;
Department of Surgery, University of Calgary, Calgary, Canada;
(BMC cancer,
v.16,
2016,
pp.850)
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989
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Abstract 4556: Matrix properties regulate 3D tumor spheroid growth and cancer drug response
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Libby, Jaxson R.;
Li, Linqing;
Walker, Sarah R.;
1University of New Hampshire, Durham, NH.;
1University of New Hampshire, Durham, NH.;
1University of New Hampshire, Durham, NH.;
(Cancer research : the official organ of the American Association for Cancer Research, Inc,
v.83,
2023,
pp.4556-4556)
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990
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Adjuvant breast cancer therapy: current status and future strategies--growth kinetics and the improved drug therapy of breast cancer.
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Norton, L;
;
(Seminars in oncology,
v.26,
1999,
pp.1-4)