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The molecular biology of cancer

edited by Stella Pelengaris and Michael Khan ; contributors, Maria Blasco ... [et al.].

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자료유형	단행본
서명/저자사항	The molecular biology of cancer / edited by Stella Pelengaris and Michael Khan ; contributors, Maria Blasco ... [et al.].
개인저자	Pelengaris, Stella. Khan, Michael. Pelengaris, Stella. Blasco, Mar Steward, William Khan, Mike Roussel, Martine Streuli, Charles Yee, Cassian Rudd, Nicky Waterhouse, Esther Witt, Bart de.
발행사항	Malden, MA : Blackwell Pub., c2006.
형태사항	ix, 531 p. : ill ; 25 cm.
ISBN	9781405118149 (pbk. : alk. paper) 1405118148 (pbk. : alk. paper)
일반주기	Includes bibliographical references and index(p.518-531).
내용주기	The burden of cancer / William Steward and Anne Thomas -- Nature and nurture in oncogenesis / Stella Pelengaris and Mike Khan -- DNA replication and the cell cycle / Stella Pelengaris and Mike Khan -- Regulation of growth: growth factors, receptors and signaling pathways / Stella Pelengaris and Mike Khan -- Oncogenes / Stella Pelengaris and Mike Khan -- Tumour suppressor genes / Martine Roussel -- Apoptosis / Stella Pelengaris and Mike Khan -- Telomeres and senescence / Maria Blasco and Mike Khan -- Genetic instability, chromosomes and repair / Stella Pelengaris and Mike Khan -- Cancer is more than a genetic condition / Stella Pelengaris and Mike Khan -- Cell adhesion, cell-cell interactions and metastases / Charles Streuli -- Tumor immunity and immunotherapy / Cassian Yee -- Angiogenesis / David Shima and Christiana Ruhrberg -- Diagnosis of cancer / William Steward and Anne Thomas -- Treatment of cancer: chemotherapy and radiotherapy / William Steward and Anne Thomas -- Caring for the cancer patient / Nicky Rudd and Esther Waterhouse -- Genomics and proteomics in cancer research and diagnosis / Bart de Witt.
일반주제명	Cancer -- Molecular aspects. Neoplasms -- genetics. Molecular Biology.
분류기호	616.994042
언어	영어

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Contents

Contributors  vi
Preface  viii
Acknowledgments  x

1. Introduction  1
    Stella Pelengaris and Mike Khan

2. The Burden of Cancer   35
    William Steward and Anne Thomas

3. Nature and Nurture in
    Oncogenesis   61
    Stella Pelengaris and Mike Khan

4. DNA Replication and the Cell
   CyCLE  88
   Stella Pelengaris and Mike Khan

5. Regulation of Growth : Growth
    Factors. Receptors, and Signaling
    Pathways   120
    Stella Pelengaris and Mike Khan

6. Oncogenes  158
    Stella Pelengaris and Mike Khan

7. Tumor Suppressor Genes   219
    Martine Roussel

8 . Apoptosis  251
    Stella Pelengaris and Mike Khan

9. Telomeres and Senescence  279
    Maria Blasco and Mike Khan

10. Genetic Instability, Chromosomes,
     and Repair   296
     Stella Pelengaris and Mike Khan

11. Cancer is More Than a Genetic
     Condition   326
     Stella Pelengaris and Mike Khan

12. Cell-matrix Adhesion, Cell-Cell
     Interactions, and Malignancy   357

13. Tumor Immunity and
      Immunotherapy   389
     Cassian Yee

14. Angiogenesis  411
     David T. Shima and Christiana
     Ruhrberg

15. Diagnosis of Cancer  424
     Anne Thomas and William Steward

16. Treatment of Cancer : Chemotherapy
      and Radiotherapy   444
      A.L.  Thomas, R.A. Sharma, and
      W.P. Steward

17. Caring ofr the Cancer Patient  464
     Nicky Rudd and Esther Waterhouse

18. Genomics and Proteomics in Cancer
      Research and Diagnosis  478
      Norbert C.J.  de Wit

      Glossary   508
      Answers to Questions   514
      Index   518

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